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"China is firmly opposed to it," Foreign Ministry spokesman Wang Wenbin said at a regular news briefing in Beijing.

"China is open today to new technology and also has advanced technology means such as communications and clouds," said Israeli. "We are looking for more cooperation in the future, and I am sure about this."

"China is one of the most important markets for Johnson & Johnson globally — it is certainly the No 1 growth engine for global business growth, and is gradually becoming an innovation engine for the world," said Aldo Denti, company group chairman of DePuy Synthes Johnson & Johnson.

"China must actively and steadily deleverage, adjust the overall floodgate of money supply and prevent the rapid increase in the macro leverage ratio," the five-year plan said.

"China is our second largest market worldwide," said Gilbert Ghostine, Firmenich CEO, adding that he expects the factory in Zhangjiagang to play a central role in the company's growth.